Resources
Terms, mechanisms and current research behind the therapies we prescribe — in plain language, from our clinical partner Heally.
Guide 01
Welcome to Weight Loss 101, your comprehensive guide to the medications used in medically supervised weight management. Dive into the science and latest research behind weight loss medications. Whether you’re a healthcare professional or someone seeking knowledge, this is your go-to resource.
Semaglutide is a pharmaceutical agent designed for the treatment of type 2 diabetes and obesity. It functions as a glucagon-like peptide-1 (GLP-1) receptor agonist, enhancing insulin secretion and delaying gastric emptying. This dual action results in improved glycemic control and promotes weight loss, proving beneficial for patients requiring management of both conditions.
The GLP-1 receptor is a protein found on the surface of certain cells in the body, including pancreatic cells. It is activated by the incretin hormone GLP-1 to enhance the release of insulin, which lowers blood sugar levels. This receptor is a critical target for drugs treating type 2 diabetes and obesity, as it also slows gastric emptying and promotes satiety.
Mounjaro, known generically as tirzepatide, is a medication for type 2 diabetes that combines the actions of GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptor agonists. It enhances blood sugar control and promotes weight loss by stimulating insulin release, inhibiting glucagon secretion, and reducing appetite.
Trulicity, with the active ingredient dulaglutide, is a once-weekly injectable prescription medicine designed for the management of type 2 diabetes. It is a GLP-1 receptor agonist that helps control blood sugar levels, supports weight loss, and is associated with cardiovascular benefits, such as reducing the risk of major cardiovascular events.
Wegovy, containing semaglutide, is a once-weekly injectable prescription medication approved for chronic weight management in adults with obesity or overweight with at least one weight-related condition. As a GLP-1 receptor agonist, it significantly reduces body weight by regulating appetite and calorie intake.
Ozempic, also based on the drug semaglutide, is an injectable prescription medicine used once weekly to improve blood sugar control in adults with type 2 diabetes. It functions as a GLP-1 receptor agonist, which aside from its glycemic regulatory roles, is also noted for its effectiveness in weight loss as a secondary benefit.
The phase III STEP clinical program has made significant strides in obesity treatment, highlighting that a 2.4 mg semaglutide dosage offers clinically meaningful and lasting weight loss, surpassing results from other available obesity agents.
In a real-world clinical setting, the effects of semaglutide treatment mirrored the weight loss results seen in randomized clinical trials, suggesting practical applicability and effectiveness.
A comprehensive study of semaglutide's effect on weight in patients managing type 2 diabetes alongside overweight or obesity.
Guide 02
Welcome to Longevity 101, your comprehensive guide to the science and strategies behind extending lifespan and improving healthspan. Explore the biology of aging, the latest research on anti-aging interventions, and how different approaches compare.
Anti-aging medicine aims to extend the lifespan and improve the quality of life through the prevention, detection, and treatment of age-related conditions. It incorporates various strategies, including lifestyle modifications, hormone replacements, and cutting-edge technologies, to combat the biological effects of aging, striving to maintain vigor and vitality into later years.
Rejuvenation involves medical and scientific interventions designed to reverse aging signs and restore youthful function and appearance to the body. By targeting the underlying causes of aging at the cellular and molecular levels, rejuvenation techniques seek to enhance overall well-being, reduce age-related diseases, and extend healthy lifespan.
Longevity refers to the science and practice of extending the human lifespan, focusing not only on adding years to life but also life to those years through improved health and vitality. Research in longevity seeks to understand the genetic, environmental, and lifestyle factors that contribute to a longer, healthier life.
Anti-aging medications are pharmaceuticals developed to slow down or reverse the aging process, targeting specific biological pathways associated with aging. These drugs aim to improve healthspan, the portion of life spent in good health, by addressing conditions like oxidative stress, inflammation, and cellular aging.
Rapamycin, a drug discovered for its immunosuppressive properties, has gained attention for its potential to extend lifespan by inhibiting the mTOR pathway, crucial in the aging process. Studies suggest rapamycin can delay aging in several species by enhancing autophagy and reducing cellular damage.
Metformin is a well-established medication for type 2 diabetes that has shown promising anti-aging effects. By improving insulin sensitivity and mimicking the benefits of caloric restriction, metformin is being researched for its potential to extend lifespan and prevent age-related diseases.
A comprehensive review of anti-aging drug development and the signal pathways they target, setting aging in context as a complex, multifactorial process leading to various chronic diseases.
Talk to a doctor who specializes in longevity. Discover the science behind living a longer, healthier life with simple, effective treatments backed by research.
Get startedResults vary. Clinical trial results apply only to the FDA-approved branded medication specifically identified and do not apply to compounded medications. All medications must be prescribed by a licensed provider based on medical necessity. Educational information only, not medical advice. Reference material provided by our clinical partner Heally. Brand names are trademarks of their respective owners. Prescription medications require evaluation by a licensed provider. Individual results vary.